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| Date | 12/31/2023 | 9/30/2023 | 6/30/2023 | 3/31/2023 | 12/31/2022 | 9/30/2022 | 6/30/2022 | 3/31/2022 | 12/31/2021 | 9/30/2021 | 6/30/2021 | 3/31/2021 | 12/31/2020 | 9/30/2020 | 6/30/2020 | 3/31/2020 | 12/31/2019 | 9/30/2019 | 6/30/2019 | 3/31/2019 | 12/31/2018 | 9/30/2018 | 8/31/2018 | 6/30/2018 | 3/31/2018 | 12/31/2017 | 9/30/2017 | 6/30/2017 | 4/30/2017 | 3/31/2017 | 12/31/2016 | 9/30/2016 | 6/30/2016 | 3/31/2016 | 12/31/2015 | 9/30/2015 | 6/30/2015 | 3/31/2015 | 12/31/2014 | 9/30/2014 | 6/30/2014 | 3/31/2014 | 12/31/2013 | 9/30/2013 | 6/30/2013 | 3/31/2013 | 12/31/2012 | 9/30/2012 | 6/30/2012 | 3/31/2012 | 12/31/2011 | 9/30/2011 | 6/30/2011 | 3/31/2011 | 12/31/2010 | 11/30/2010 | 7/31/2010 | 4/30/2010 | 12/31/2009 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash and Cash Equivalents | $135,117,000.00 | $86,855,000.00 | $102,352,000.00 | $104,690,000.00 | $111,097,000.00 | $127,465,000.00 | $135,858,000.00 | $179,947,000.00 | $190,300,776.00 | $174,863,565.00 | $174,102,382.00 | $149,932,387.00 | $115,917,807.00 | $143,495,266.00 | $64,741,921.00 | $11,275,214.00 | $8,962,686.00 | $10,972,482.00 | $41,671,738.00 | $44,300,170.00 | $33,718,713.00 | $7,964,002.00 | -- | $4,170,770.00 | $4,559,894.00 | $8,769,465.00 | $17,116,845.00 | $8,367,774.00 | -- | $15,782,402.00 | $153,994,922.00 | $69,106,979.00 | $23,157,883.00 | $14,235,621.00 | $15,569,813.00 | $17,389,409.00 | $18,411,839.00 | $15,724,956.00 | $18,643,351.00 | $19,620,392.00 | $11,265,082.00 | $9,534,720.00 | $10,480,979.00 | $15,943,399.00 | $15,789,909.00 | $12,873,411.00 | $12,701,517.00 | $14,726,328.00 | $11,776,921.00 | $15,304,189.00 | $11,236,771.00 | $10,406,076.00 | $14,160,598.00 | $9,708,249.00 | $11,785,327.00 | -- | -- | -- | $2,673,567.00 |
| Accounts Receivable Net Current | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $1,000,000.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $4,874,632.00 | -- | -- | -- | $5,367,130.00 | -- | -- | -- | -- |
| Inventory | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Prepaid Expenses and Other Current Assets | $6,917,000.00 | $7,615,000.00 | $5,822,000.00 | $3,978,000.00 | $5,358,000.00 | $4,790,000.00 | $4,619,000.00 | $5,039,000.00 | $7,952,690.00 | $7,294,360.00 | $9,413,070.00 | $5,950,999.00 | $1,926,675.00 | $1,309,044.00 | $1,020,876.00 | $698,905.00 | $470,228.00 | $410,148.00 | $688,862.00 | $505,949.00 | $548,094.00 | $443,929.00 | -- | $677,478.00 | $1,449,364.00 | $994,332.00 | $1,007,032.00 | $1,448,818.00 | -- | $467,642.00 | $464,797.00 | $509,857.00 | $418,636.00 | $463,873.00 | $181,714.00 | $196,478.00 | $316,014.00 | $446,240.00 | $199,194.00 | $661,360.00 | $550,979.00 | $401,448.00 | $231,491.00 | $209,514.00 | $667,850.00 | $614,388.00 | $547,245.00 | $363,742.00 | $675,047.00 | $802,080.00 | $380,395.00 | -- | -- | -- | $1,354,912.00 | -- | -- | -- | -- |
| Total Current Assets | $209,626,000.00 | $152,964,000.00 | $169,532,000.00 | $173,111,000.00 | $192,813,000.00 | $211,004,000.00 | $195,504,000.00 | $191,093,000.00 | $204,126,115.00 | $218,263,032.00 | $238,624,889.00 | $245,191,823.00 | $230,257,209.00 | $218,131,544.00 | $87,970,418.00 | $39,636,971.00 | $39,394,749.00 | $41,623,918.00 | $46,105,173.00 | $49,414,052.00 | $39,372,134.00 | $11,966,030.00 | -- | $11,865,956.00 | $19,920,760.00 | $23,465,867.00 | $26,122,474.00 | $16,995,600.00 | -- | $18,292,087.00 | $222,269,826.00 | $138,036,311.00 | $25,398,806.00 | $16,136,637.00 | $17,226,866.00 | $18,245,550.00 | $19,905,673.00 | $22,739,443.00 | $19,250,632.00 | $20,585,419.00 | $12,433,457.00 | $11,586,064.00 | $14,339,108.00 | $17,766,238.00 | $21,692,450.00 | $19,067,512.00 | $19,795,845.00 | $20,378,622.00 | $20,683,102.00 | $21,528,724.00 | $19,613,006.00 | -- | -- | -- | $23,583,729.00 | -- | -- | -- | -- |
| Property Plant and Equipement | $651,000.00 | $765,000.00 | $882,000.00 | $1,007,000.00 | $1,081,000.00 | $1,172,000.00 | $1,236,000.00 | $1,337,000.00 | $1,447,786.00 | $4,718,146.00 | $4,751,010.00 | $5,198,052.00 | $1,056,920.00 | $1,041,920.00 | $1,024,640.00 | $1,062,834.00 | $1,104,208.00 | $1,162,715.00 | $1,222,130.00 | $1,282,752.00 | $1,342,802.00 | $1,407,080.00 | -- | $1,475,935.00 | $1,374,927.00 | $603,146.00 | $280,093.00 | $293,233.00 | -- | $87,937.00 | $120,944.00 | $153,823.00 | $183,695.00 | $196,143.00 | $233,694.00 | $248,270.00 | $308,256.00 | $324,018.00 | $325,772.00 | $362,458.00 | $386,541.00 | $380,572.00 | $386,068.00 | $429,506.00 | $460,101.00 | $456,842.00 | $483,976.00 | $553,081.00 | $625,534.00 | $701,982.00 | $788,666.00 | -- | -- | -- | $1,178,416.00 | -- | -- | -- | -- |
| Intangible Assets Net | -- | -- | -- | -- | $12,419,000.00 | $12,419,000.00 | $12,419,000.00 | $12,419,000.00 | $12,418,967.00 | $12,993,575.00 | $12,956,112.00 | $12,879,247.00 | $12,823,846.00 | $12,794,806.00 | $12,785,655.00 | $12,737,735.00 | $12,732,195.00 | $12,741,656.00 | $13,760,216.00 | $13,762,199.00 | $13,851,924.00 | $38,339,086.00 | -- | $38,349,189.00 | $39,345,901.00 | $38,722,270.00 | $38,586,399.00 | $38,132,266.00 | -- | -- | $14,954,717.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Goodwill | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $9,334,904.00 | $35,398,960.00 | -- | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | $2,348,453.00 | -- | -- | -- | $2,348,453.00 | -- | -- | -- | -- |
| Other Assets | $363,000.00 | $425,000.00 | $483,000.00 | $546,000.00 | $615,000.00 | $682,000.00 | $747,000.00 | $811,000.00 | $871,976.00 | $931,904.00 | $928,839.00 | $115,300.00 | $73,413.00 | $87,195.00 | $100,980.00 | $114,764.00 | $128,547.00 | $142,331.00 | $156,115.00 | $169,898.00 | $183,682.00 | $1,149,185.00 | -- | $411,250.00 | $225,133.00 | $238,917.00 | $22,248.00 | $22,247.00 | -- | -- | -- | -- | -- | $53,384.00 | $53,384.00 | $53,384.00 | $53,384.00 | $53,384.00 | $53,384.00 | $53,384.00 | $55,032.00 | $59,132.00 | $65,660.00 | $74,594.00 | $85,907.00 | $99,578.00 | $113,130.00 | $130,709.00 | $150,479.00 | $174,525.00 | $53,384.00 | -- | -- | -- | -- | -- | -- | -- | -- |
| Total Assets | $210,640,000.00 | $166,573,000.00 | $183,316,000.00 | $187,083,000.00 | $206,928,000.00 | $225,277,000.00 | $209,906,000.00 | $205,660,000.00 | $218,864,844.00 | $236,906,657.00 | $257,260,850.00 | $264,250,758.00 | $245,115,213.00 | $232,995,320.00 | $102,543,767.00 | $54,233,130.00 | $54,058,020.00 | $56,387,923.00 | $61,976,014.00 | $65,373,830.00 | $54,750,542.00 | $52,861,381.00 | -- | $52,102,330.00 | $60,866,721.00 | $63,030,200.00 | $74,346,118.00 | $90,842,306.00 | -- | $20,728,477.00 | $224,739,223.00 | $140,538,587.00 | $27,930,954.00 | $18,734,617.00 | $19,862,397.00 | $20,895,657.00 | $22,615,766.00 | $25,465,298.00 | $21,978,241.00 | $23,349,714.00 | $15,223,483.00 | $14,374,221.00 | $17,139,289.00 | $20,618,791.00 | $24,586,911.00 | $21,972,385.00 | $22,741,404.00 | $23,410,865.00 | $23,807,568.00 | $24,753,684.00 | $22,803,509.00 | -- | -- | -- | $27,199,045.00 | -- | -- | -- | -- |
| Accounts Payable | $2,070,000.00 | $3,046,000.00 | $4,035,000.00 | $5,238,000.00 | $4,804,000.00 | $1,419,000.00 | $2,872,000.00 | $2,205,000.00 | $2,034,493.00 | $6,083.00 | $1,421,192.00 | $418,243.00 | $612,293.00 | $874,885.00 | $195,217.00 | $929,629.00 | $18,232.00 | $49,884.00 | $270,097.00 | $14,753.00 | $372,860.00 | $150,738.00 | -- | $245,250.00 | $513,168.00 | $129,075.00 | $495,064.00 | $1,130,797.00 | -- | $839,465.00 | $926,529.00 | $614,543.00 | $711,106.00 | $166,357.00 | $521,122.00 | $306,172.00 | $208,456.00 | $536,994.00 | $391,396.00 | $282,024.00 | $437,382.00 | $471,803.00 | $1,128,172.00 | $1,159,179.00 | $2,992,549.00 | $1,289,627.00 | $1,697,280.00 | $1,846,614.00 | $2,062,718.00 | $1,410,516.00 | $1,445,700.00 | -- | -- | -- | $3,128,203.00 | -- | -- | -- | -- |
| Accrued Liabilities | -- | -- | -- | -- | -- | -- | -- | -- | -- | $19,120,902.00 | $7,674,536.00 | $9,405,649.00 | $11,408,154.00 | $5,418,831.00 | $4,089,749.00 | $5,115,694.00 | $3,904,767.00 | $2,311,824.00 | $3,046,567.00 | $3,434,519.00 | $4,082,949.00 | $6,532,924.00 | -- | $5,305,868.00 | $4,528,125.00 | $3,625,257.00 | -- | -- | -- | -- | $2,972,745.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Total Current Liabilities | $16,541,000.00 | $16,176,000.00 | $15,602,000.00 | $19,351,000.00 | $21,635,000.00 | $20,248,000.00 | $15,371,000.00 | $20,792,000.00 | $19,730,133.00 | $27,642,596.00 | $15,982,878.00 | $17,813,330.00 | $19,238,890.00 | $33,289,485.00 | $23,021,990.00 | $12,336,513.00 | $8,537,874.00 | $7,003,973.00 | $5,750,992.00 | $6,051,720.00 | $6,437,976.00 | $13,178,193.00 | -- | $15,782,258.00 | $14,371,973.00 | $14,352,610.00 | $17,277,574.00 | $14,865,686.00 | -- | $2,677,169.00 | $205,280,132.00 | $4,155,547.00 | $3,680,250.00 | $3,108,133.00 | $3,213,280.00 | $3,223,700.00 | $4,279,854.00 | $5,442,053.00 | $3,704,096.00 | $5,243,671.00 | $4,358,871.00 | $6,048,819.00 | $9,803,577.00 | $9,265,225.00 | $11,366,467.00 | $12,029,620.00 | $11,067,564.00 | $10,860,115.00 | $10,262,122.00 | $10,982,817.00 | $6,951,703.00 | -- | -- | -- | $14,988,340.00 | -- | -- | -- | -- |
| Long Term Debt | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $568,321.00 | $500,000.00 | $572,770.00 | -- | -- | -- | -- | $599,927.00 | $590,185.00 | $570,545.00 | -- | -- | $525,950.00 | -- | -- | -- | -- | -- | -- | -- | -- | $993,322.00 | $1,239,734.00 | $1,485,384.00 | -- | $2,000,002.00 | -- | -- | -- | $2,500,000.00 | $2,500,000.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Additional Paid-in Capital | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $240,151,146.00 | $239,490,378.00 | $239,064,585.00 | $238,780,633.00 | $235,979,613.00 | $224,104,547.00 | $221,125,757.00 | $217,877,117.00 | $217,471,662.00 | $215,392,930.00 | $210,877,892.00 | $210,495,905.00 | $210,101,716.00 | $209,662,510.00 | $209,111,489.00 | $208,525,917.00 | -- | -- | -- | $200,847,468.00 | -- | -- | -- | -- |
| Accumulated Other Comprehensive Loss | $-5,004,000.00 | $-5,124,000.00 | $-5,180,000.00 | $-5,101,000.00 | $-5,227,000.00 | $-5,303,000.00 | $-5,160,000.00 | $-5,040,000.00 | $-5,040,163.00 | $-5,040,163.00 | $-5,038,240.00 | $-5,039,381.00 | $-5,044,517.00 | $-5,042,272.00 | $-5,031,703.00 | $-5,052,591.00 | $-5,020,156.00 | $-5,021,210.00 | $-5,040,163.00 | $-5,040,163.00 | $-5,040,163.00 | $-5,040,163.00 | -- | $-5,040,163.00 | $-3,961,515.00 | $-4,576,986.00 | $-4,709,973.00 | $-5,738,006.00 | -- | -- | $-1,052.00 | $12,346.00 | -- | -- | -- | -- | -- | -- | $-229,528.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Accumulated Deficit | $-466,331,000.00 | $-434,690,000.00 | $-414,019,000.00 | $-397,958,000.00 | $-377,884,000.00 | $-356,224,000.00 | $-332,708,000.00 | $-312,601,000.00 | $-293,171,423.00 | $-269,282,102.00 | $-235,771,414.00 | $-210,944,707.00 | $-186,420,599.00 | $-175,798,822.00 | $-158,028,687.00 | $-141,261,771.00 | $-137,376,122.00 | $-133,279,497.00 | $-122,340,185.00 | $-118,953,297.00 | $-116,855,991.00 | $-92,348,368.00 | -- | $-89,997,219.00 | $-80,858,377.00 | $-77,684,839.00 | $-68,853,850.00 | $-38,948,613.00 | -- | $-32,067,449.00 | $-29,869,852.00 | $-107,671,444.00 | $-216,906,457.00 | $-224,950,931.00 | $-223,724,025.00 | $-222,485,625.00 | $-221,160,857.00 | $-218,819,925.00 | $-220,283,320.00 | $-217,653,920.00 | $-213,025,485.00 | $-212,586,365.00 | $-210,327,925.00 | $-205,903,216.00 | $-201,957,329.00 | $-200,720,957.00 | $-198,609,572.00 | $-197,339,824.00 | $-197,125,888.00 | $-196,369,345.00 | $-193,689,457.00 | -- | -- | -- | $-189,891,884.00 | -- | -- | -- | -- |
| Total Stockholders' Equity | $194,099,000.00 | $150,397,000.00 | $167,714,000.00 | $167,732,000.00 | $185,293,000.00 | $205,029,000.00 | $194,535,000.00 | $184,868,000.00 | $199,134,711.00 | $209,264,061.00 | $241,277,972.00 | $246,437,428.00 | $225,876,323.00 | $199,705,835.00 | $79,521,777.00 | $41,896,617.00 | $45,520,146.00 | $49,383,950.00 | $56,225,022.00 | $59,322,110.00 | $48,312,566.00 | $39,683,188.00 | -- | $35,809,989.00 | $40,540,232.00 | $39,395,823.00 | $48,830,244.00 | $75,976,620.00 | -- | $18,051,308.00 | $19,459,091.00 | $136,383,040.00 | $24,250,704.00 | $15,626,484.00 | $16,649,117.00 | $17,671,957.00 | $18,335,912.00 | $20,023,245.00 | $18,274,145.00 | $18,106,043.00 | $10,864,612.00 | $8,325,402.00 | $7,335,712.00 | $11,353,566.00 | $13,220,444.00 | $9,942,765.00 | $11,673,840.00 | $12,550,750.00 | $13,545,446.00 | $13,770,867.00 | $15,851,806.00 | -- | -- | -- | $12,210,705.00 | -- | -- | -- | $3,152,399.00 |
| Controlling Interest in Subsidiaries | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Total Liabilities and Equity | $210,640,000.00 | $166,573,000.00 | $183,316,000.00 | $187,083,000.00 | $206,928,000.00 | $225,277,000.00 | $209,906,000.00 | $205,660,000.00 | $218,864,844.00 | $236,906,657.00 | $257,260,850.00 | $264,250,758.00 | $245,115,213.00 | $232,995,320.00 | $102,543,767.00 | $54,233,130.00 | $54,058,020.00 | $56,387,923.00 | $61,976,014.00 | $65,373,830.00 | $54,750,542.00 | $52,861,381.00 | -- | $52,102,330.00 | $60,866,721.00 | $63,030,200.00 | $74,346,118.00 | $90,842,306.00 | -- | $20,728,477.00 | $224,739,223.00 | $140,538,587.00 | $27,930,954.00 | $18,734,617.00 | $19,862,397.00 | $20,895,657.00 | $22,615,766.00 | $25,465,298.00 | $21,978,241.00 | $23,349,714.00 | $15,223,483.00 | $14,374,221.00 | $17,139,289.00 | $20,618,791.00 | $24,586,911.00 | $21,972,385.00 | $22,741,404.00 | $23,410,865.00 | $23,807,568.00 | $24,753,684.00 | $22,803,509.00 | -- | -- | -- | $27,199,045.00 | -- | -- | -- | -- |
| Date | 12/31/2023 | 9/30/2023 | 6/30/2023 | 3/31/2023 | 12/31/2022 | 9/30/2022 | 6/30/2022 | 3/31/2022 | 12/31/2021 | 9/30/2021 | 6/30/2021 | 3/31/2021 | 12/31/2020 | 9/30/2020 | 6/30/2020 | 3/31/2020 | 12/31/2019 | 9/30/2019 | 6/30/2019 | 3/31/2019 | 12/31/2018 | 9/30/2018 | 8/31/2018 | 6/30/2018 | 3/31/2018 | 12/31/2017 | 9/30/2017 | 6/30/2017 | 4/30/2017 | 3/31/2017 | 12/31/2016 | 9/30/2016 | 6/30/2016 | 3/31/2016 | 12/31/2015 | 9/30/2015 | 6/30/2015 | 3/31/2015 | 12/31/2014 | 9/30/2014 | 6/30/2014 | 3/31/2014 | 12/31/2013 | 9/30/2013 | 6/30/2013 | 3/31/2013 | 12/31/2012 | 9/30/2012 | 6/30/2012 | 3/31/2012 | 12/31/2011 | 9/30/2011 | 6/30/2011 | 3/31/2011 | 12/31/2010 | 11/30/2010 | 7/31/2010 | 4/30/2010 | 12/31/2009 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Revenues | $426,000.00 | $389,000.00 | $27,000.00 | $21,000.00 | $-68,000.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $24,266,274.00 | -- | -- | -- | $20,993,605.00 | -- | -- | -- | -- |
| Cost of Revenues | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Gross Profit | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Research and Development | $65,799,000.00 | $18,388,000.00 | $30,502,000.00 | $17,249,000.00 | $70,538,000.00 | $51,359,000.00 | $15,993,000.00 | $15,104,000.00 | $74,541,115.00 | $29,205,739.00 | $25,150,312.00 | $11,877,900.00 | $49,774,328.00 | $40,823,756.00 | $23,781,781.00 | $7,187,531.00 | $17,765,553.00 | $8,729,697.00 | $6,162,768.00 | $3,217,671.00 | $18,459,310.00 | $4,728,726.00 | -- | $4,918,961.00 | $5,746,971.00 | $18,406,329.00 | $5,905,552.00 | $8,040,851.00 | -- | $725,797.00 | $4,836,035.00 | $1,236,692.00 | $1,143,182.00 | $1,029,131.00 | $5,133,512.00 | $1,125,865.00 | $1,222,527.00 | $1,613,627.00 | $9,319,828.00 | $1,728,929.00 | $5,799,687.00 | $3,427,000.00 | $15,290,142.00 | $11,192,403.00 | $8,636,020.00 | $5,233,475.00 | $19,509,629.00 | $5,138,622.00 | $9,624,012.00 | $4,705,357.00 | $21,219,853.00 | $16,688,703.00 | $5,984,098.00 | $5,820,374.00 | $20,875,536.00 | -- | -- | -- | -- |
| Selling, General, and Administrative | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Total Operating Expenses | $96,355,000.00 | $22,902,000.00 | $39,793,000.00 | $21,780,000.00 | $87,672,000.00 | $24,754,000.00 | $39,934,000.00 | $19,531,000.00 | $101,324,397.00 | $74,062,052.00 | $40,700,385.00 | $15,699,320.00 | $62,983,768.00 | $49,921,267.00 | $28,659,054.00 | $9,519,448.00 | $27,266,336.00 | $22,378,424.00 | $5,176,913.00 | $5,284,153.00 | $53,165,578.00 | $6,692,459.00 | -- | $7,852,943.00 | $8,685,541.00 | $62,783,581.00 | $47,410,185.00 | $11,865,877.00 | -- | $3,987,394.00 | $16,494,543.00 | $4,983,674.00 | $2,618,998.00 | $2,260,130.00 | $14,043,460.00 | $11,836,486.00 | $9,022,099.00 | $5,907,662.00 | $20,381,510.00 | $4,958,481.00 | $4,828,804.00 | $6,144,391.00 | $28,751,815.00 | $6,687,324.00 | $5,777,129.00 | $7,565,872.00 | $31,442,277.00 | $8,486,503.00 | $7,775,202.00 | $7,739,748.00 | $35,992,005.00 | $28,669,788.00 | $20,387,817.00 | $10,877,657.00 | $44,547,162.00 | -- | -- | -- | -- |
| Loss from Operations | $-95,929,000.00 | $-62,306,000.00 | $-18,007,000.00 | $-21,759,000.00 | $-87,740,000.00 | $-24,752,000.00 | $-20,395,000.00 | $-19,499,000.00 | $-96,914,041.00 | $-72,929,354.00 | $-39,725,246.00 | $-14,861,804.00 | $-54,798,741.00 | $-18,324,222.00 | $-25,724,724.00 | $-7,306,754.00 | $-21,464,935.00 | $-17,152,824.00 | $-3,550,884.00 | $-2,328,561.00 | $-42,834,410.00 | $-15,488,429.00 | -- | $-5,435,803.00 | $-5,994,561.00 | $-52,045,259.00 | $-39,480,701.00 | $-8,528,333.00 | -- | $-3,183,323.00 | $-11,264,347.00 | $-3,989,789.00 | $-507,744.00 | $-1,254,436.00 | $-940,469.00 | $-2,462,331.00 | $-1,964,867.00 | $1,161,084.00 | $-10,191,305.00 | $-3,996,030.00 | $-1,169,871.00 | $-2,401,866.00 | $-5,067,563.00 | $-3,199,182.00 | $-1,481,729.00 | $-1,090,734.00 | $-1,427,113.00 | $-1,790,377.00 | $-1,458,204.00 | $-1,590,696.00 | $-11,725,731.00 | $-3,021,914.00 | $-7,621,255.00 | $-4,539,935.00 | $-23,553,557.00 | -- | -- | -- | -- |
| Loss Before Income Taxes | $-88,447,000.00 | $-56,806,000.00 | -- | -- | $-84,910,000.00 | $-63,250,000.00 | -- | -- | $-97,090,824.00 | $-33,510,688.00 | $-39,690,815.00 | $-14,864,108.00 | $-54,461,501.00 | $-18,252,152.00 | $-25,477,226.00 | $-7,131,528.00 | $-20,578,631.00 | $-10,997,812.00 | $-5,484,194.00 | $-2,097,306.00 | $-45,320,946.00 | $-3,180,542.00 | -- | $-10,635,935.00 | $-4,165,176.00 | $-52,063,765.00 | $-31,438,027.00 | $-8,682,873.00 | -- | $-4,578,781.00 | $-11,086,812.00 | $-8,024,985.00 | $-1,617,070.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Earnings Per Share Basic | $-1.66 | $-1.10 | $-0.72 | $-0.40 | $-1.81 | $-1.37 | $-0.90 | $-0.44 | $-2.35 | $-0.81 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $2.97 | $1.68 | $0.11 | $-0.02 | $-0.02 | $-0.02 | $-0.04 | $0.02 | $-0.04 | $-0.08 | $-0.01 | $-0.04 | $-0.08 | $-0.08 | $-0.02 | $-0.04 | $-0.03 | -- | $-0.02 | $-0.06 | $0.02 | -- | $-0.05 | $-0.04 | -- | -- | -- | -- | -- |
| Weighted Average Shares Basic | 53,246,937 | 51,495,957 | 50,410,184 | 50,125,685 | 46,926,349 | 45,881,547 | 47,502,599 | 43,969,481 | 41,283,498 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 65,306,962 | 65,001,584 | 64,737,820 | 64,404,396 | 63,986,013 | 64,187,618 | 63,745,834 | 63,633,290 | 57,535,325 | -- | -- | 53,044,119 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Earnings Per Share Diluted | $-1.66 | $-1.10 | $-0.32 | $-0.39 | $-1.81 | $-0.48 | $-0.42 | $-0.44 | $-2.35 | $-1.79 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $1.15 | $1.79 | $0.12 | $-0.02 | $-0.02 | $-0.02 | $-0.04 | $0.02 | $-0.04 | $-0.08 | $-0.01 | $-0.04 | $-0.08 | $-0.08 | $-0.02 | $-0.04 | $-0.03 | -- | $-0.02 | $-0.06 | $0.02 | -- | $-0.05 | $-0.04 | -- | -- | -- | -- | -- |
| Weighted Average Shares Diluted | 53,246,937 | 53,633,354 | 50,410,184 | 50,125,685 | 46,926,349 | 49,286,535 | 44,150,835 | 43,969,481 | 41,283,498 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 65,657,802 | 65,322,158 | 65,206,075 | 64,404,396 | 63,986,013 | 63,858,500 | 63,691,214 | 63,979,859 | 57,535,325 | -- | -- | 53,044,119 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Common Stock Shares Authorized | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 200,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | -- | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | 100,000,000 | -- | -- | -- | 100,000,000 | -- | -- | -- | -- |
| Common Stock Shares Outstanding | 70,677,400 | 52,858,920 | 52,657,661 | 49,286,710 | 49,199,845 | 49,161,637 | 46,372,105 | 43,219,896 | 40,993,768 | 39,702,768 | 39,693,524 | 38,257,180 | 37,142,946 | 33,073,035 | 26,553,886 | 15,359,502 | 15,312,167 | 15,338,072 | 13,450,751 | 13,450,680 | 9,078,238 | 1,725,630 | -- | 37,363,965 | 22,250,337 | 18,103,691 | 15,627,081 | 15,424,891 | -- | 68,815,195 | 67,726,458 | 66,423,033 | 64,785,846 | 64,444,725 | 64,382,086 | 64,358,834 | 63,912,193 | 63,674,326 | 63,603,303 | 62,215,986 | 55,525,710 | 53,773,705 | 52,304,426 | 52,297,580 | 51,173,919 | 48,416,483 | 48,352,651 | 48,345,984 | 48,345,984 | 48,314,510 | 48,236,172 | -- | -- | -- | 46,238,244 | -- | -- | -- | -- |
| Common Stock Value | $7,000.00 | $5,000.00 | $5,000.00 | $5,000.00 | $5,000.00 | $5,000.00 | $5,000.00 | $4,000.00 | $4,090.00 | $3,959.00 | $3,956.00 | $3,810.00 | $3,697.00 | $3,289.00 | $2,635.00 | $1,514.00 | $1,508.00 | $1,502.00 | $1,313.00 | $1,313.00 | $876.00 | $173.00 | -- | $3,737.00 | $2,225.00 | $1,810.00 | $1,563.00 | $1,542.00 | -- | $6,882.00 | $6,773.00 | $6,642.00 | $6,479.00 | $6,444.00 | $6,438.00 | $6,436.00 | $6,391.00 | $6,367.00 | $6,360.00 | $6,222.00 | $5,553.00 | $5,377.00 | $5,230.00 | $5,230.00 | $5,117.00 | $4,842.00 | $4,835.00 | $4,835.00 | $4,835.00 | $4,832.00 | $4,824.00 | -- | -- | -- | $4,624.00 | -- | -- | -- | -- |
| Common Stock Par Or Stated Value Per Share | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | -- | -- | -- | $0.00 | -- | -- | -- | -- |
| Payments Of Dividends Common Stock | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Preferred Stock Shares Authorized | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | 1,000,000 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Preferred Stock Shares Outstanding | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Preferred Stock Value | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Preferred Stock Par Or Stated Value Per Share | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Share Price | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | $3.50 | -- | -- | $3.50 | $1.40 | $1.50 | -- |