PursePoor.com

All individual numbers are from the SEC provided Financial Statement and Notes Data Sets. No guarantee is made for their accuracy.

ADAGENE INC.: Last Reported 12/31/2022

Business Address

4F, BUILDING C14, NO. 218, XINGHU STREET
SUZHOU INDUSTRIAL PARK
JIANGSU , CN 00000

Mailing Address

4F, BUILDING C14, NO. 218, XINGHU STREET
SUZHOU INDUSTRIAL PARK
JIANGSU , CN 00000

Phone Number: 86-512-87773632 / State Incorporated: / Fiscal Year End 12 /31

Financials: AccountsPayableCurrent

	Date	Value
1	12/31/2022	$3,666,124.00
2	12/31/2021	$3,321,615.00
3	12/31/2020	$1,809,975.00
4	12/31/2019	$712,714.00

Financials: AccruedProfessionalFeesCurrent

	Date	Value
1	12/31/2022	$1,647,490.00
2	12/31/2021	$935,434.00
3	12/31/2020	$3,459,430.00
4	12/31/2019	$145,157.00

Financials: AccruedUtilitiesCurrent

	Date	Value
1	12/31/2022	$40,718.00
2	12/31/2021	$8,685.00
3	12/31/2020	$459.00
4	12/31/2019	$4,595.00

Financials: AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment

	Date	Value
1	12/31/2022	$5,909,305.00
2	12/31/2021	$5,322,264.00
3	12/31/2020	$4,290,431.00
4	12/31/2019	$3,205,690.00

Financials: AccumulatedOtherComprehensiveIncomeLossNetOfTax

	Date	Value
1	12/31/2022	$-849,305.00
2	12/31/2021	$-93,981.00
3	12/31/2020	$-350,981.00
4	12/31/2019	$-344,894.00

Financials: AdditionalPaidInCapital

	Date	Value
1	12/31/2022	$342,739,268.00
2	12/31/2021	$336,099,931.00
3	12/31/2020	$23,786,652.00
4	12/31/2019	$6,789,542.00

Financials: AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue

	Date	Value
1	12/31/2022	$10,520,282.00
2	12/31/2021	$18,679,658.00
3	12/31/2020	$10,129,541.00
4	12/31/2019	$611,711.00
5	12/31/2018	$126,540.00

Financials: AllocatedShareBasedCompensationExpense

	Date	Value
1	12/31/2022	$10,520,282.00
2	12/31/2021	$18,679,658.00
3	12/31/2020	$10,129,541.00
4	12/31/2019	$611,711.00
5	12/31/2018	$126,540.00

Financials: AmountOfRestrictedNetAssetsForConsolidatedAndUnconsolidatedSubsidiaries

	Date	Value
1	12/31/2022	$1,860,667.00
2	12/31/2021	$1,860,667.00
3	12/31/2020	$1,267,900.00
4	12/31/2019	$1,267,900.00

Financials: Assets

	Date	Value
1	12/31/2022	$152,399,845.00
2	12/31/2021	$189,510,726.00
3	12/31/2020	$84,262,737.00
4	12/31/2019	$105,889,499.00

Financials: AssetsCurrent

	Date	Value
1	12/31/2022	$149,315,433.00
2	12/31/2021	$185,953,834.00
3	12/31/2020	$79,097,378.00
4	12/31/2019	$103,922,947.00

Financials: CashAndCashEquivalentsAtCarryingValue

	Date	Value
1	12/31/2022	$143,758,678.00
2	12/31/2021	$174,391,243.00
3	12/31/2020	$75,150,998.00
4	12/31/2019	$92,532,788.00

Financials: CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents

	Date	Value
1	12/31/2022	$143,758,678.00
2	12/31/2021	$174,391,243.00
3	12/31/2020	$75,150,998.00
4	12/31/2019	$92,532,788.00
5	12/31/2018	$16,058,455.00
6	12/31/2017	$8,736,104.00

Financials: CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect

	Date	Value
1	12/31/2022	$-30,632,565.00
2	12/31/2021	$99,240,245.00
3	12/31/2020	$-17,381,790.00
4	12/31/2019	$76,474,333.00
5	12/31/2018	$7,322,351.00

Financials: CommitmentsAndContingencies

	Date	Value
1	12/31/2022	--
2	12/31/2021	--
3	12/31/2020	--
4	12/31/2019	--

Financials: CommonStockParOrStatedValuePerShare

	Date	Value
1	12/31/2022	$0.00
2	12/31/2021	$0.00
3	12/31/2020	$0.00
4	12/31/2019	$0.00

Financials: CommonStockSharesAuthorized

	Date	Value
1	12/31/2022	$640,000,000.00
2	12/31/2021	$640,000,000.00
3	12/31/2020	$500,000,000.00
4	12/31/2019	$500,000,000.00

Financials: CommonStockSharesIssued

	Date	Value
1	12/31/2022	$54,065,709.00
2	12/31/2021	$54,595,667.00
3	12/31/2020	$18,888,070.00
4	12/31/2019	$15,193,136.00

Financials: CommonStockSharesOutstanding

	Date	Value
1	12/31/2022	$54,065,709.00
2	12/31/2021	$54,595,667.00
3	12/31/2020	$16,603,070.00
4	12/31/2019	$15,193,136.00

Financials: CommonStockValue

	Date	Value
1	12/31/2022	$5,497.00
2	12/31/2021	$5,627.00
3	12/31/2020	$1,889.00
4	12/31/2019	$1,519.00

Financials: ComprehensiveIncomeNetOfTax

	Date	Value
1	12/31/2022	$-80,727,171.00
2	12/31/2021	$-72,920,935.00
3	12/31/2020	$-42,403,366.00
4	12/31/2019	$-16,366,509.00
5	12/31/2018	$-15,277,472.00

Financials: ContractWithCustomerLiabilityCurrent

	Date	Value
1	12/31/2022	$15,107,276.00
2	12/31/2021	$5,500,000.00
3	12/31/2020	$725,536.00
4	12/31/2019	$993,378.00

Financials: CurrentFederalTaxExpenseBenefit

	Date	Value
1	12/31/2022	$672,064.00
2	12/31/2021	$1,290,009.00

Financials: CurrentIncomeTaxExpenseBenefit

	Date	Value
1	12/31/2022	$503,218.00
2	12/31/2021	$1,657,450.00

Financials: CurrentStateAndLocalTaxExpenseBenefit

	Date	Value
1	12/31/2022	$-168,846.00
2	12/31/2021	$367,441.00

Financials: DebtCurrent

	Date	Value
1	12/31/2022	$13,618,873.00
2	12/31/2021	$4,497,545.00
3	12/31/2020	$5,015,402.00
4	12/31/2019	$1,039,248.00

Financials: DebtLongtermAndShorttermCombinedAmount

	Date	Value
1	12/31/2022	$27,765,414.00
2	12/31/2021	$7,489,374.00
3	12/31/2020	$7,980,965.00
4	12/31/2019	$2,555,116.00

Financials: DeferredFederalIncomeTaxExpenseBenefit

	Date	Value
1	12/31/2022	$-96,804.00
2	12/31/2021	$96,804.00

Financials: DeferredIncomeTaxExpenseBenefit

	Date	Value
1	12/31/2022	$-44,163.00
2	12/31/2021	$44,163.00

Financials: DeferredIncomeTaxLiabilities

	Date	Value
1	12/31/2022	$82,959.00
2	12/31/2021	$120,858.00

Financials: DeferredStateAndLocalIncomeTaxExpenseBenefit

	Date	Value
1	12/31/2022	$52,641.00
2	12/31/2021	$-52,641.00

Financials: DeferredTaxAssetsGross

	Date	Value
1	12/31/2022	$9,607,456.00
2	12/31/2021	$5,083,834.00
3	12/31/2020	$1,512,394.00
4	12/31/2019	$938,875.00
5	12/31/2018	$739,930.00

Financials: DeferredTaxAssetsInProcessResearchAndDevelopment

	Date	Value
1	12/31/2022	$756,197.00

Financials: DeferredTaxAssetsInventory

	Date	Value
1	12/31/2022	$94,954.00
2	12/31/2021	$95,589.00

Financials: DeferredTaxAssetsNet

	Date	Value
1	12/31/2022	$82,959.00
2	12/31/2021	$76,695.00

Financials: DeferredTaxAssetsOperatingLossCarryforwards

	Date	Value
1	12/31/2022	$8,217,976.00
2	12/31/2021	$4,949,000.00
3	12/31/2020	$1,504,966.00
4	12/31/2019	$928,989.00
5	12/31/2018	$735,717.00

Financials: DeferredTaxAssetsTaxCreditCarryforwards

	Date	Value
1	12/31/2022	$391,843.00

Financials: DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAccruedLiabilities

	Date	Value
1	12/31/2022	$29,702.00

Financials: DeferredTaxAssetsUnrealizedCurrencyLosses

	Date	Value
1	12/31/2022	$116,238.00
2	12/31/2021	$39,166.00

Financials: DeferredTaxAssetsValuationAllowance

	Date	Value
1	12/31/2022	$9,524,497.00
2	12/31/2021	$5,007,139.00
3	12/31/2020	$2,729,721.00
4	12/31/2019	$938,875.00
5	12/31/2018	$739,930.00
6	12/31/2017	$134,290.00

Financials: DeferredTaxLiabilitiesPropertyPlantAndEquipment

	Date	Value
1	12/31/2022	$82,959.00
2	12/31/2021	$120,858.00

Financials: DefinedContributionPlanCostRecognized

	Date	Value
1	12/31/2022	$2,984,251.00
2	12/31/2021	$2,223,493.00
3	12/31/2020	$622,377.00
4	12/31/2019	$1,145,165.00

Financials: DepositsAssetsCurrent

	Date	Value
1	12/31/2022	$2,970,421.00
2	12/31/2021	$1,873,843.00
3	12/31/2020	$1,646,446.00
4	12/31/2019	$970,394.00

Financials: DepreciationDepletionAndAmortization

	Date	Value
1	12/31/2022	$1,145,995.00
2	12/31/2021	$1,125,032.00
3	12/31/2020	$858,408.00
4	12/31/2019	$816,686.00
5	12/31/2018	$909,002.00

Financials: DueFromRelatedPartiesCurrent

	Date	Value
1	12/31/2022	$619,432.00
2	12/31/2021	$4,506,670.00
3	12/31/2020	$132,396.00
4	12/31/2019	$1,433,186.00

Financials: DueToRelatedPartiesCurrent

	Date	Value
1	12/31/2022	$19,323,337.00
2	12/31/2021	$10,466,061.00
3	12/31/2020	$2,535,358.00
4	12/31/2019	$1,895,779.00

Financials: EarningsPerShareBasic

	Date	Value
1	12/31/2022	$-1.48
2	12/31/2021	$-1.46
3	12/31/2020	$-2.67
4	12/31/2019	$-1.10
5	12/31/2018	$-0.94

Financials: EarningsPerShareDiluted

	Date	Value
1	12/31/2022	$-1.48
2	12/31/2021	$-1.46
3	12/31/2020	$-2.67
4	12/31/2019	$-1.10
5	12/31/2018	$-0.94

Financials: EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate

	Date	Value
1	12/31/2022	$0.25
2	12/31/2021	$0.15
3	12/31/2020	$0.25
4	12/31/2019	$0.15

Financials: EffectiveIncomeTaxRateReconciliationFdiiAmount

	Date	Value
1	12/31/2022	$487,183.00

Financials: EffectiveIncomeTaxRateReconciliationTaxCutsAndJobsActOf2017Amount

	Date	Value
1	12/31/2022	$10,560,029.00
2	12/31/2021	$10,549,985.00
3	12/31/2020	$5,286,487.00
4	12/31/2019	$2,492,721.00

Financials: EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations

	Date	Value
1	12/31/2022	$842,195.00
2	12/31/2021	$-192,352.00
3	12/31/2020	$-364,177.00
4	12/31/2019	$77,544.00
5	12/31/2018	$38,703.00

Financials: EmployeeRelatedLiabilitiesCurrent

	Date	Value
1	12/31/2022	$1,104,365.00
2	12/31/2021	$3,229,794.00
3	12/31/2020	$2,390,025.00
4	12/31/2019	$2,370,523.00

Financials: EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions

	Date	Value
1	12/31/2022	$23,635,444.00
2	12/31/2021	$30,607,079.00
3	12/31/2020	$34,096,227.00

Financials: ForeignCurrencyTransactionGainLossBeforeTax

	Date	Value
1	12/31/2022	$2,555,325.00
2	12/31/2021	$-603,459.00
3	12/31/2020	$-644,693.00
4	12/31/2019	$21,867.00
5	12/31/2018	$12,698.00

Financials: GeneralAndAdministrativeExpense

	Date	Value
1	12/31/2022	$11,873,867.00
2	12/31/2021	$14,439,962.00
3	12/31/2020	$10,314,536.00
4	12/31/2019	$3,437,900.00
5	12/31/2018	$2,765,134.00

Financials: ImpairmentOfLongLivedAssetsHeldForUse

	Date	Value
1	12/31/2022	--
2	12/31/2021	--
3	12/31/2020	--
4	12/31/2019	--

Financials: IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest

	Date	Value
1	12/31/2022	$-79,512,792.00
2	12/31/2021	$-71,476,322.00
3	12/31/2020	$-42,397,279.00
4	12/31/2019	$-16,432,308.00
5	12/31/2018	$-15,266,184.00

Financials: IncomeTaxesPaidNet

	Date	Value
1	12/31/2022	$2,433,241.00

Financials: IncomeTaxExpenseBenefit

	Date	Value
1	12/31/2022	$459,055.00
2	12/31/2021	$1,701,613.00

Financials: IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance

	Date	Value
1	12/31/2022	$4,517,358.00
2	12/31/2021	$2,277,418.00
3	12/31/2020	$1,790,846.00
4	12/31/2019	$198,945.00
5	12/31/2018	$605,640.00

Financials: IncomeTaxReconciliationChangeInEnactedTaxRate

	Date	Value
1	12/31/2022	$7,951,279.00
2	12/31/2021	$7,147,633.00
3	12/31/2020	$4,239,728.00

Financials: IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate

	Date	Value
1	12/31/2022	$-19,878,198.00
2	12/31/2021	$-10,721,448.00
3	12/31/2020	$-1,073,105.00
4	12/31/2019	$-2,464,846.00
5	12/31/2018	$-30,560.00

Financials: IncomeTaxReconciliationNondeductibleExpense

	Date	Value
1	12/31/2022	$3,695.00
2	12/31/2021	$1,054.00
3	12/31/2020	$1,238.00
4	12/31/2019	$3,306.00
5	12/31/2018	$4,010.00

Financials: IncomeTaxReconciliationOtherAdjustments

	Date	Value
1	12/31/2022	$10,263.00
2	12/31/2021	$-127,880.00

Financials: IncomeTaxReconciliationStateAndLocalIncomeTaxes

	Date	Value
1	12/31/2022	$76,127.00
2	12/31/2021	$291,500.00

Financials: IncomeTaxReconciliationTaxCreditsResearch

	Date	Value
1	12/31/2022	$569,575.00

Financials: IncreaseDecreaseInAccountsPayable

	Date	Value
1	12/31/2022	$344,509.00
2	12/31/2021	$1,511,640.00
3	12/31/2020	$1,097,261.00
4	12/31/2019	$153,737.00
5	12/31/2018	$389,124.00

Financials: IncreaseDecreaseInAccountsReceivable

	Date	Value
1	12/31/2022	$-3,000,000.00
2	12/31/2021	$3,000,000.00
3	12/31/2020	$-480,000.00
4	12/31/2019	$480,000.00

Financials: IncreaseDecreaseInAccruedIncomeTaxesPayable

	Date	Value
1	12/31/2022	$-1,657,450.00
2	12/31/2021	$1,657,450.00

Financials: IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities

	Date	Value
1	12/31/2022	$-823,928.00
2	12/31/2021	$1,057,491.00
3	12/31/2020	$1,243,150.00
4	12/31/2019	$-34,277.00
5	12/31/2018	$-913,495.00

Financials: IncreaseDecreaseInContractWithCustomerLiability

	Date	Value
1	12/31/2022	$9,607,276.00
2	12/31/2021	$4,774,464.00
3	12/31/2020	$-267,842.00
4	12/31/2019	$993,378.00

Financials: IncreaseDecreaseInDeferredIncomeTaxes

	Date	Value
1	12/31/2022	$44,163.00
2	12/31/2021	$-44,163.00

Financials: IncreaseDecreaseInDueFromRelatedParties

	Date	Value
1	12/31/2022	$-3,887,238.00
2	12/31/2021	$4,374,274.00
3	12/31/2020	$-1,300,790.00
4	12/31/2019	$704,253.00
5	12/31/2018	$-268,671.00

Financials: IncreaseDecreaseInDueToRelatedParties

	Date	Value
1	12/31/2022	$8,857,276.00
2	12/31/2021	$7,930,703.00
3	12/31/2020	$639,579.00
4	12/31/2019	$-1,778,469.00
5	12/31/2018	$2,135,397.00

Financials: IncreaseDecreaseInOperatingLeaseLiability

	Date	Value
1	12/31/2022	$-280,465.00

Financials: IncreaseDecreaseInOtherNoncurrentAssets

	Date	Value
1	12/31/2022	$40,297.00
2	12/31/2021	$24,210.00
3	12/31/2020	$13,292.00
4	12/31/2019	$38,040.00
5	12/31/2018	$28,808.00

Financials: IncreaseDecreaseInOtherNoncurrentLiabilities

	Date	Value
1	12/31/2022	$-29,732.00
2	12/31/2020	$91,955.00
3	12/31/2019	$-142,114.00

Financials: IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets

	Date	Value
1	12/31/2022	$881,402.00
2	12/31/2021	$231,287.00
3	12/31/2020	$2,337,011.00
4	12/31/2019	$-111,516.00
5	12/31/2018	$1,337,063.00

Financials: InterestExpense

	Date	Value
1	12/31/2022	$693,323.00
2	12/31/2021	$363,762.00
3	12/31/2020	$202,165.00
4	12/31/2019	$138,096.00
5	12/31/2018	$91,085.00

Financials: InterestPaidNet

	Date	Value
1	12/31/2022	$603,680.00
2	12/31/2021	$359,569.00
3	12/31/2020	$202,165.00
4	12/31/2019	$142,058.00
5	12/31/2018	$91,085.00

Financials: InvestmentIncomeNonoperating

	Date	Value
1	12/31/2022	$377,501.00
2	12/31/2021	$76,166.00
3	12/31/2020	$629,288.00
4	12/31/2019	$922,680.00
5	12/31/2018	$710,711.00

Financials: LesseeOperatingLeaseLiabilityPaymentsDue

	Date	Value
1	12/31/2022	$212,426.00

Financials: LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths

	Date	Value
1	12/31/2022	$157,603.00

Financials: LesseeOperatingLeaseLiabilityPaymentsDueYearTwo

	Date	Value
1	12/31/2022	$54,823.00

Financials: LesseeOperatingLeaseLiabilityUndiscountedExcessAmount

	Date	Value
1	12/31/2022	$6,609.00

Financials: Liabilities

	Date	Value
1	12/31/2022	$69,309,495.00
2	12/31/2021	$32,952,013.00
3	12/31/2020	$19,203,286.00
4	12/31/2019	$8,697,151.00

Financials: LiabilitiesAndStockholdersEquity

	Date	Value
1	12/31/2022	$152,399,845.00
2	12/31/2021	$189,510,726.00
3	12/31/2020	$84,262,737.00
4	12/31/2019	$105,889,499.00

Financials: LiabilitiesCurrent

	Date	Value
1	12/31/2022	$55,080,402.00
2	12/31/2021	$29,821,914.00
3	12/31/2020	$16,145,768.00
4	12/31/2019	$7,181,283.00

Financials: LongTermDebtCurrent

	Date	Value
1	12/31/2022	$2,850,128.00
2	12/31/2021	$1,376,319.00
3	12/31/2020	$1,183,926.00
4	12/31/2019	$322,525.00

Financials: LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour

	Date	Value
1	12/31/2022	$10,022,112.00
2	12/31/2021	$1,133,210.00

Financials: LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree

	Date	Value
1	12/31/2022	$4,124,429.00
2	12/31/2021	$1,133,210.00
3	12/31/2020	$1,685,850.00

Financials: LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo

	Date	Value
1	12/31/2022	$13,618,873.00
2	12/31/2021	$1,858,619.00
3	12/31/2020	$1,279,713.00

Financials: LongTermDebtNoncurrent

	Date	Value
1	12/31/2022	$14,146,541.00
2	12/31/2021	$2,991,829.00
3	12/31/2020	$2,965,563.00
4	12/31/2019	$1,515,868.00

Financials: LongTermLoansFromBank

	Date	Value
1	12/31/2022	$14,146,541.00
2	12/31/2021	$2,991,829.00
3	12/31/2020	$2,965,563.00
4	12/31/2019	$1,515,868.00

Financials: NetCashProvidedByUsedInFinancingActivities

	Date	Value
1	12/31/2022	$17,822,973.00
2	12/31/2021	$145,357,142.00
3	12/31/2020	$4,439,376.00
4	12/31/2019	$69,694,477.00
5	12/31/2018	$51,057,850.00

Financials: NetCashProvidedByUsedInInvestingActivities

	Date	Value
1	12/31/2022	$-686,046.00
2	12/31/2021	$-2,509,926.00
3	12/31/2020	$7,072,731.00
4	12/31/2019	$24,855,868.00
5	12/31/2018	$-29,509,537.00

Financials: NetCashProvidedByUsedInOperatingActivities

	Date	Value
1	12/31/2022	$-48,611,687.00
2	12/31/2021	$-43,414,619.00
3	12/31/2020	$-28,529,720.00
4	12/31/2019	$-18,153,556.00
5	12/31/2018	$-14,264,665.00

Financials: NetIncomeLoss

	Date	Value
1	12/31/2022	$-79,971,847.00
2	12/31/2021	$-73,177,935.00
3	12/31/2020	$-42,397,279.00
4	12/31/2019	$-16,432,308.00
5	12/31/2018	$-15,266,184.00

Financials: NetIncomeLossAvailableToCommonStockholdersBasic

	Date	Value
1	12/31/2022	$-79,971,847.00
2	12/31/2021	$-73,206,488.00
3	12/31/2020	$-42,645,392.00
4	12/31/2019	$-16,678,492.00
5	12/31/2018	$-14,302,843.00

Financials: OperatingIncomeLoss

	Date	Value
1	12/31/2022	$-83,920,683.00
2	12/31/2021	$-72,364,089.00
3	12/31/2020	$-43,151,658.00
4	12/31/2019	$-19,169,650.00
5	12/31/2018	$-17,334,526.00

Financials: OperatingLeaseLiability

	Date	Value
1	12/31/2022	$205,817.00

Financials: OperatingLeaseLiabilityCurrent

	Date	Value
1	12/31/2022	$151,983.00

Financials: OperatingLeaseLiabilityNoncurrent

	Date	Value
1	12/31/2022	$53,834.00

Financials: OperatingLeasePayments

	Date	Value
1	12/31/2022	$313,929.00

Financials: OperatingLeaseRightOfUseAsset

	Date	Value
1	12/31/2022	$191,877.00

Financials: OperatingLeaseRightOfUseAssetAmortizationExpense

	Date	Value
1	12/31/2022	$283,276.00

Financials: OperatingLeaseWeightedAverageDiscountRatePercent

	Date	Value
1	12/31/2022	$0.05

Financials: OperatingLossCarryforwards

	Date	Value
1	12/31/2022	$50,742,841.00
2	12/31/2021	$27,453,623.00

Financials: OtherAssetsCurrent

	Date	Value
1	12/31/2022	$804,992.00
2	12/31/2021	$619,901.00
3	12/31/2020	$259,757.00
4	12/31/2019	$67,866.00

Financials: OtherAssetsNoncurrent

	Date	Value
1	12/31/2022	$109,572.00
2	12/31/2021	$69,275.00
3	12/31/2020	$3,098,234.00
4	12/31/2019	$87,227.00

Financials: OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent

	Date	Value
1	12/31/2022	$-755,324.00
2	12/31/2021	$257,000.00
3	12/31/2020	$-6,087.00
4	12/31/2019	$65,799.00
5	12/31/2018	$-11,288.00

Financials: OtherComprehensiveIncomeForeignCurrencyTranslationAdjustmentTaxPortionAttributableToParent

	Date	Value
1	12/31/2022	--
2	12/31/2021	--
3	12/31/2020	--
4	12/31/2019	--
5	12/31/2018	--

Financials: OtherLiabilitiesCurrent

	Date	Value
1	12/31/2022	$71,197.00
2	12/31/2021	$143,060.00
3	12/31/2020	$145,664.00
4	12/31/2019	$19,889.00

Financials: OtherLiabilitiesNoncurrent

	Date	Value
1	12/31/2022	$28,718.00
2	12/31/2021	$94,107.00
3	12/31/2020	$91,955.00

Financials: OtherNonoperatingIncome

	Date	Value
1	12/31/2022	$2,168,388.00
2	12/31/2021	$1,778,822.00
3	12/31/2020	$971,949.00
4	12/31/2019	$723,476.00
5	12/31/2018	$901,713.00

Financials: PaymentsForRepurchaseOfCommonStock

	Date	Value
1	12/31/2022	$3,976,681.00
2	12/31/2021	$2,361,576.00

Financials: PaymentsToAcquireProductiveAssets

	Date	Value
1	12/31/2022	$690,938.00
2	12/31/2021	$2,509,926.00
3	12/31/2020	$935,199.00
4	12/31/2019	$151,829.00
5	12/31/2018	$514,703.00

Financials: PreferredStockSharesIssued

	Date	Value
1	12/31/2022	--
2	12/31/2021	--

Financials: PreferredStockSharesOutstanding

	Date	Value
1	12/31/2022	--
2	12/31/2021	--

Financials: PrepaidExpenseAndOtherAssetsCurrent

	Date	Value
1	12/31/2022	$4,937,323.00
2	12/31/2021	$4,055,921.00
3	12/31/2020	$3,813,984.00
4	12/31/2019	$1,476,973.00

Financials: PrepaidExpenseCurrent

	Date	Value
1	12/31/2022	$1,161,910.00
2	12/31/2021	$1,562,177.00
3	12/31/2020	$1,907,781.00
4	12/31/2019	$211,435.00

Financials: ProceedsFromIssuanceOfDebt

	Date	Value
1	12/31/2022	$25,830,030.00
2	12/31/2021	$4,386,860.00
3	12/31/2020	$6,083,650.00
4	12/31/2019	$2,651,874.00
5	12/31/2018	$2,417,868.00

Financials: ProceedsFromSaleOfProductiveAssets

	Date	Value
1	12/31/2022	$4,892.00
2	12/31/2020	$7,930.00
3	12/31/2019	$7,697.00
4	12/31/2018	$5,166.00

Financials: ProceedsFromStockOptionsExercised

	Date	Value
1	12/31/2022	$323,212.00
2	12/31/2021	$231,521.00
3	12/31/2020	$140,928.00
4	12/31/2019	$459,796.00

Financials: ProfitLoss

	Date	Value
1	12/31/2022	$-79,971,847.00
2	12/31/2021	$-73,177,935.00
3	12/31/2020	$-42,397,279.00
4	12/31/2019	$-16,432,308.00
5	12/31/2018	$-15,266,184.00

Financials: PropertyPlantAndEquipmentGross

	Date	Value
1	12/31/2022	$8,692,268.00
2	12/31/2021	$8,809,881.00
3	12/31/2020	$6,357,556.00
4	12/31/2019	$5,085,015.00

Financials: PropertyPlantAndEquipmentNet

	Date	Value
1	12/31/2022	$2,782,963.00
2	12/31/2021	$3,487,617.00
3	12/31/2020	$2,067,125.00
4	12/31/2019	$1,879,325.00

Financials: RepaymentsOfDebt

	Date	Value
1	12/31/2022	$4,353,588.00
2	12/31/2021	$5,089,717.00
3	12/31/2020	$1,063,670.00
4	12/31/2019	$2,417,192.00
5	12/31/2018	$1,360,051.00

Financials: ResearchAndDevelopmentExpense

	Date	Value
1	12/31/2022	$81,339,540.00
2	12/31/2021	$68,099,385.00
3	12/31/2020	$33,538,035.00
4	12/31/2019	$16,211,750.00
5	12/31/2018	$16,080,560.00

Financials: RetainedEarningsAccumulatedDeficit

	Date	Value
1	12/31/2022	$-258,805,106.00
2	12/31/2021	$-178,833,259.00
3	12/31/2020	$-105,655,324.00
4	12/31/2019	$-63,258,045.00

Financials: RevenueFromContractWithCustomerExcludingAssessedTax

	Date	Value
1	12/31/2022	$9,292,724.00
2	12/31/2021	$10,175,258.00
3	12/31/2020	$700,913.00
4	12/31/2019	$480,000.00
5	12/31/2018	$1,511,168.00

Financials: RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability

	Date	Value
1	12/31/2022	$217,227.00

Financials: ShareBasedCompensation

	Date	Value
1	12/31/2022	$10,520,282.00
2	12/31/2021	$18,679,658.00
3	12/31/2020	$10,129,541.00
4	12/31/2019	$611,711.00
5	12/31/2018	$126,540.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate

	Date	Value
1	12/31/2022	--
2	12/31/2021	--
3	12/31/2020	--
4	12/31/2019	--

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum

	Date	Value
1	12/31/2022	$0.75
2	12/31/2021	$0.76
3	12/31/2020	$0.73
4	12/31/2019	$0.71

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum

	Date	Value
1	12/31/2022	$0.74
2	12/31/2021	$0.73
3	12/31/2020	$0.72
4	12/31/2019	$0.68

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum

	Date	Value
1	12/31/2022	$0.04
2	12/31/2021	$0.02
3	12/31/2020	$0.01
4	12/31/2019	$0.03

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum

	Date	Value
1	12/31/2022	$0.02
2	12/31/2021	$0.01
3	12/31/2020	$0.01
4	12/31/2019	$0.02

Financials: SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1

	Date	Value
1	12/31/2022	$55,880.00
2	12/31/2021	$874,180.00
3	12/31/2020	$4,859,836.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber

	Date	Value
1	12/31/2022	$2,070,533.00
2	12/31/2021	$1,486,318.00
3	12/31/2020	$393,424.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice

	Date	Value
1	12/31/2022	$6.35
2	12/31/2021	$5.87
3	12/31/2020	$0.75

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod

	Date	Value
1	12/31/2022	$964,789.00
2	12/31/2021	$145,550.00
3	12/31/2020	$190,000.00
4	12/31/2019	$46,800.00
5	12/31/2018	$274,500.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross

	Date	Value
1	12/31/2022	$2,640,598.00
2	12/31/2021	$1,894,119.00
3	12/31/2020	$6,313,373.00
4	12/31/2019	$372,500.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue

	Date	Value
1	12/31/2022	$2.13
2	12/31/2021	$8.39
3	1/31/2021	$7.85
4	12/31/2020	$7.01
5	12/31/2019	$5.46

Financials: SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedWeightedAverageGrantDateFairValue

	Date	Value
1	12/31/2022	$7.57
2	12/31/2021	$7.71
3	12/31/2020	$6.91
4	12/31/2019	$5.75
5	12/31/2018	$5.71

Financials: SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue

	Date	Value
1	12/31/2022	$5.16
2	12/31/2021	$7.38
3	12/31/2020	$6.65
4	12/31/2019	$3.67
5	12/31/2018	$2.80
6	12/31/2017	$3.75

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue

	Date	Value
1	12/31/2022	$94,990.00
2	12/31/2021	$2,619,574.00
3	12/31/2020	$33,410,968.00
4	12/31/2019	$6,328,171.00
5	12/31/2018	$3,734,644.00
6	12/31/2017	$4,907,569.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber

	Date	Value
1	12/31/2022	$6,286,912.00
2	12/31/2021	$4,809,078.00
3	12/31/2020	$3,294,467.00
4	12/31/2019	$866,028.00
5	12/31/2018	$574,328.00
6	12/31/2017	$848,828.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice

	Date	Value
1	12/31/2022	$4.80
2	12/31/2021	$5.91
3	12/31/2020	$1.75
4	12/31/2019	$0.65
5	12/31/2018	$0.30
6	12/31/2017	$0.38

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue

	Date	Value
1	12/31/2022	$94,990.00
2	12/31/2021	$2,619,574.00
3	12/31/2020	$33,410,968.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber

	Date	Value
1	12/31/2022	$6,286,912.00
2	12/31/2021	$4,809,078.00
3	12/31/2020	$3,294,467.00

Financials: ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice

	Date	Value
1	12/31/2022	$4.80
2	12/31/2021	$5.91
3	12/31/2020	$1.75

Financials: SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1

	Date	Value
1	12/31/2022	$11,929,903.00
2	12/31/2021	$13,833,856.00
3	12/31/2020	$8,430,085.00
4	12/31/2019	$366,113.00
5	12/31/2018	$165,609.00

Financials: ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice

	Date	Value
1	12/31/2022	$2.08
2	12/31/2021	$0.99
3	12/31/2020	$1.93
4	12/31/2019	$0.55

Financials: ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice

	Date	Value
1	12/31/2022	$6.75
2	12/31/2021	$3.02
3	12/31/2020	$1.70
4	12/31/2019	$1.22
5	12/31/2018	$0.55

Financials: ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice

	Date	Value
1	12/31/2022	$3.28
2	12/31/2021	$12.31
3	1/31/2021	$13.85
4	12/31/2020	$2.00
5	12/31/2019	$1.26

Financials: ShortTermBankLoansAndNotesPayable

	Date	Value
1	12/31/2022	$10,768,745.00
2	12/31/2021	$3,121,226.00
3	12/31/2020	$3,831,476.00
4	12/31/2019	$716,723.00

Financials: ShortTermLeaseCost

	Date	Value
1	12/31/2022	$34,729.00

Financials: StockholdersEquity

	Date	Value
1	12/31/2022	$83,090,350.00
2	12/31/2021	$156,558,713.00
3	12/31/2020	$-89,389,956.00
4	12/31/2019	$-57,008,946.00
5	12/31/2018	$-41,026,664.00
6	12/31/2017	$-25,652,886.00

Financials: StockIssuedDuringPeriodSharesStockOptionsExercised

	Date	Value
1	12/31/2022	$197,975.00
2	12/31/2021	$233,958.00
3	12/31/2020	$3,694,934.00
4	12/31/2019	$34,000.00

Financials: StockIssuedDuringPeriodValueShareBasedCompensation

	Date	Value
1	12/31/2022	$391,995.00
2	12/31/2021	$416,751.00

Financials: StockIssuedDuringPeriodValueStockOptionsExercised

	Date	Value
1	12/31/2022	$323,212.00
2	12/31/2021	$226,781.00
3	12/31/2020	$140,928.00
4	12/31/2019	$18,700.00

Financials: TaxesPayableCurrent

	Date	Value
1	12/31/2022	$349,039.00
2	12/31/2021	$62,270.00
3	12/31/2020	$63,919.00

Financials: TreasuryStockCommonShares

	Date	Value
1	12/31/2022	$1.00
2	12/31/2021	$94,074.00

Financials: TreasuryStockCommonValue

	Date	Value
1	12/31/2022	$4.00
2	12/31/2021	$619,605.00

Financials: TreasuryStockValueAcquiredCostMethod

	Date	Value
1	12/31/2022	$3,976,681.00
2	12/31/2021	$2,361,576.00

Financials: ValuationAllowanceDeferredTaxAssetChangeInAmount

	Date	Value
1	12/31/2022	$4,517,358.00
2	12/31/2021	$2,277,418.00
3	12/31/2020	$573,519.00
4	12/31/2019	$198,945.00
5	12/31/2018	$605,640.00

Financials: WeightedAverageNumberOfDilutedSharesOutstanding

	Date	Value
1	12/31/2022	$54,135,084.00
2	12/31/2021	$50,032,009.00
3	12/31/2020	$15,950,698.00
4	12/31/2019	$15,178,232.00
5	12/31/2018	$15,159,136.00

Financials: WeightedAverageNumberOfSharesOutstandingBasic

	Date	Value
1	12/31/2022	$54,135,084.00
2	12/31/2021	$50,032,009.00
3	12/31/2020	$15,950,698.00
4	12/31/2019	$15,178,232.00
5	12/31/2018	$15,159,136.00